NFL Week 12 Best Bets
Week 12 is where pricing discipline separates bettors. The market is sharp, public bias is strong, and late-season urgency starts creeping into game plans. Your edge is rarely “finding a winner”—it’s getting the right number, shopping the best price, and avoiding bad entries on games you don’t need.
Use this page as your Week 12 hub. Start with the strongest positions on NFL Best Bets, compare spreads/totals/moneylines on the football odds board, and track who’s consistently beating the market on the Best Bets leaderboard. Track closing line value (CLV) every week—if you’re not beating the close, you’re paying extra tax.
2025/26 NFL Week 12 Schedule
By Week 12, the season is a grind. Attrition, short rest, travel, and weather variance start shaping both spreads and totals. This is also when teams reveal their true decision-making profiles: conservative vs aggressive, clock-control vs tempo, and how they protect a lead. Those tendencies matter for ATS outcomes and totals as much as raw yardage.
Paste your Week 12 schedule list and this becomes the table-ready scan for every kickoff window, including primetime and any standalone games.
| Date | Matchup | Time | Location |
|---|---|---|---|
| Thursday, November 20, 2025 | Buffalo @ Houston | 7:15 PM | NRG Stadium, Houston, TX |
| Sunday, November 23, 2025 | Pittsburgh @ Chicago | 12:00 PM | Soldier Field, Chicago, IL |
| Sunday, November 23, 2025 | New England @ Cincinnati | 12:00 PM | Paycor Stadium, Cincinnati, OH |
| Sunday, November 23, 2025 | New York @ Detroit | 12:00 PM | Ford Field, Detroit, MI |
| Sunday, November 23, 2025 | Minnesota @ Green Bay | 12:00 PM | Lambeau Field, Green Bay, WI |
| Sunday, November 23, 2025 | Seattle @ Tennessee | 12:00 PM | Nissan Stadium, Nashville, TN |
| Sunday, November 23, 2025 | Indianapolis @ Kansas City | 12:00 PM | GEHA Field at Arrowhead Stadium, Kansas City, MO |
| Sunday, November 23, 2025 | New York @ Baltimore | 12:00 PM | M&T Bank Stadium, Baltimore, MD |
| Sunday, November 23, 2025 | Cleveland @ Las Vegas | 3:05 PM | Allegiant Stadium, Las Vegas, NV |
| Sunday, November 23, 2025 | Jacksonville @ Arizona | 3:05 PM | State Farm Stadium, Glendale, AZ |
| Sunday, November 23, 2025 | Philadelphia @ Dallas | 3:25 PM | AT&T Stadium, Arlington, TX |
| Sunday, November 23, 2025 | Atlanta @ New Orleans | 3:25 PM | Caesars Superdome, New Orleans, LA |
| Sunday, November 23, 2025 | Tampa Bay @ Los Angeles | 7:20 PM | SoFi Stadium, Inglewood, CA |
| Monday, November 24, 2025 | Carolina @ San Francisco | 7:15 PM | Levi’s Stadium, Santa Clara, CA |
NFL Week 12 Picks
This section is for playable positions only—spreads (ATS), totals, and moneylines—kept tight so the best edges stand out. Week 12 is a “number quality” week: lines are efficient and mistakes are expensive. A half-point, a key number, or a better price can be the difference between a profitable week and a break-even grind.
When picks are added here, cap it at 6–10 and tie each play to a defined range. If the spread crosses key numbers or the total moves with worse juice, treat it as a different bet. Shop lines, track CLV, and don’t chase steam.
Today’s Sports Picks
Kick Off the Season with Expert Picks from AskTheBookie
AskTheBookie membership is built for bettors who want sharper execution: picks backed by matchup edges, market movement notes that help you time entries, and a disciplined approach to spreads/totals/moneylines that doesn’t rely on narrative. The leaderboard keeps it accountable so you can track who’s consistently beating the market over time.
To unlock full access, join or sign in here and follow picks as they post throughout the week. When you’re ready to build your Week 12 card around the best numbers available, return to NFL Best Bets and prioritize positions that still grade as playable at current prices.
