NFL Week 3 Best Bets
Week 3 is where early-season perception starts to harden—and that’s exactly where bettors can get sloppy. Two games is enough for the market to “decide” what a team is, even when the underlying truth is still forming. This page keeps your Week 3 work clean: schedule first, picks second, and the leaderboard always one click away.
Use it as a process. Start with the highest-confidence spots on our NFL Best Bets page, compare prices and alternates on the football odds board, and track who’s earning trust on the Best Bets leaderboard. If you’re serious about long-term results, treat line shopping and closing line value (CLV) like non-negotiables—especially while the market is still correcting.
2025/26 NFL Week 3 Schedule
Week 3 betting is a balancing act: you have more real data than Week 1, but the market can still overreact to a couple of turnovers, a lopsided fourth quarter, or one headline performance. This is a strong week to stay price-driven—if the number has moved past your cutoff, don’t chase it. Protect CLV, narrow your card, and let the best numbers dictate your volume.
| Date | Matchup | Time (ET) | Location |
|---|---|---|---|
| Thu, Sept 18, 2025 | Miami Dolphins at Buffalo Bills | 8:15 PM | Orchard Park, New York |
| Sun, Sept 21, 2025 | Atlanta Falcons at Carolina Panthers | 1:00 PM | Charlotte, North Carolina |
| Sun, Sept 21, 2025 | Green Bay Packers at Cleveland Browns | 1:00 PM | Cleveland, Ohio |
| Sun, Sept 21, 2025 | Houston Texans at Jacksonville Jaguars | 1:00 PM | Jacksonville, Florida |
| Sun, Sept 21, 2025 | Pittsburgh Steelers at New England Patriots | 1:00 PM | Foxborough, Massachusetts |
| Sun, Sept 21, 2025 | Los Angeles Rams at Philadelphia Eagles | 1:00 PM | Philadelphia, Pennsylvania |
| Sun, Sept 21, 2025 | New York Jets at Tampa Bay Buccaneers | 1:00 PM | Tampa, Florida |
| Sun, Sept 21, 2025 | Cincinnati Bengals at Minnesota Vikings | 1:00 PM | Minneapolis, Minnesota |
| Sun, Sept 21, 2025 | Indianapolis Colts at Tennessee Titans | 1:00 PM | Nashville, Tennessee |
| Sun, Sept 21, 2025 | Las Vegas Raiders at Washington Commanders | 1:00 PM | Landover, Maryland |
| Sun, Sept 21, 2025 | Denver Broncos at Los Angeles Chargers | 4:05 PM | Inglewood, California |
| Sun, Sept 21, 2025 | New Orleans Saints at Seattle Seahawks | 4:05 PM | Seattle, Washington |
| Sun, Sept 21, 2025 | Dallas Cowboys at Chicago Bears | 4:25 PM | Chicago, Illinois |
| Sun, Sept 21, 2025 | Arizona Cardinals at San Francisco 49ers | 4:25 PM | Santa Clara, California |
| Sun, Sept 21, 2025 | Kansas City Chiefs at New York Giants | 8:20 PM | East Rutherford, New Jersey |
| Mon, Sept 22, 2025 | Detroit Lions at Baltimore Ravens | 8:15 PM | Baltimore, Maryland |
NFL Week 3 Picks
This section is built for decisions, not decoration: spreads (ATS), totals, and moneylines organized around number quality and timing. Week 3 is a prime “shop your edge” week—books sharpen quickly, and small differences (a half-point, a better total price, a cleaner moneyline) can be the difference between a good bet and a bad entry.
When picks are added here, keep it tight and playable. Every entry should be something you’d still take at a defined range, not a fragile lean that dies after one move. If you’re not beating the number, you’re donating margin—track your CLV and stay ruthless about pass vs play.
Today’s Sports Picks
Kick Off the Season with Expert Picks from AskTheBookie
AskTheBookie membership is built for bettors who want clarity: not just what to bet, but why it’s playable, what market signals matter, and how spreads/totals/moneylines should be approached as the week develops. You’ll get matchup edges, market movement notes, and a tighter workflow so you’re not forcing action on a crowded slate.
To unlock the full experience, join or sign in here and follow the card as it updates. Then head back to NFL Best Bets to build a Week 3 plan around your best numbers and cleanest entries.
